| Robert Newton | Bill Sikes |
| Alec Guinness | Fagin |
| Kay Walsh | Nancy |
| Francis L. Sullivan | Mr. Bumble |
| Henry Stephenson | Mr. Brownlow |
| Mary Clare | Mrs. Corney |
| Anthony Newley | Artful Dodger |
| Josephine Stuart | Oliver's Mother |
| Ralph Truman | Monks |
| Kathleen Harrison | Mrs. Sowerberry |
| Gibb McLaughlin | Mr. Sowerberry |
| Amy Veness | Mrs. Bedwin |
| Frederick Lloyd | Dr. Grimwig |
| John Howard Davies | Oliver Twist |
| Henry Edwards | Police Official |
| Ivor Barnard | Chairman of the Board |
| Maurice Denham | Chief of Police |
| Michael Dear | Noah Claypole |
| Michael Ripper | Barney |
| Peter Bull | Landlord of 'Three Cripples' |
| Deidre Doyle | Old Sally Thingummy |
| Diana Dors | Charlotte |
| Kenneth Downey | Workhouse Master (as Kenneth Downy) |
| W.G. Fay | Bookseller |
| Edie Martin | Annie |
| Fay Middleton | Martha |
| Graveley Edwards | Mr. Fang |
| John Potter | Charlie Bates |
| Maurice Jones | Workhouse Doctor |
| Hattie Jacques | Singer at 'Three Cripples' |
| Betty Paul | Singer at 'Three Cripples' |
| Johnny Briggs | Undetermined Minor Role (uncredited) |
| Erik Chitty | Workhouse Board Member (uncredited) |
| Arthur Mullard | Undetermined Minor Role (uncredited) |
| Nosher Powell | Undetermined Minor Role (uncredited) |
| Eustace Shipman | Doctor Who Delivers Oliver (uncredited) |
| Paul Stockman | Fagin's gang member (uncredited) |
| Dennis Wyndham | Man In Street Who Punches Oliver (uncredited) |
