| John Wayne | Capt. Ralls |
| Gail Russell | Angelique Desaix |
| Gig Young | Samuel 'Sam' Rosen |
| Adele Mara | Teleia Van Schreeven |
| Luther Adler | Mayrant Ruysdaal Sidneye |
| Eduard Franz | Harmenszoon Van Schreeven |
| Grant Withers | Capt. Wilde Youngeur |
| Henry Daniell | Jacques Desaix |
| Paul Fix | Antonio 'Ripper' Arrezo |
| Dennis Hoey | Capt. Munsey |
| Jeff Corey | Mr. Loring |
| Erskine Sanford | Dr. van Arken |
| Duke Kahanamoku | Ua Nuke |
| Fred Aldrich | Seaman (uncredited) |
| Fernando Alvarado | Maru (uncredited) |
| Jose Alvarado | Taluna (uncredited) |
| George Barrows | Seaman (uncredited) |
| Henry Brandon | Kurinua (uncredited) |
| David Clarke | Mullins (uncredited) |
| James Dime | Seaman (uncredited) |
| Fred Fox | Ship's Surgeon (uncredited) |
| Fred Graham | Sailor in Fight (uncredited) |
| Vic Groves | Seaman (uncredited) |
| Myron Healey | Seaman on 'Red Witch' (uncredited) |
| Mailoa Kalili | Seaman (uncredited) |
| Al Kikume | Native Servant (uncredited) |
| Fred Libby | Lookout Sailor (uncredited) |
| Harold Lishman | Kharma (uncredited) |
| Rory Mallinson | Officer (uncredited) |
| Grant Means | Dirk (uncredited) |
| Frank Mills | Seaman (uncredited) |
| Forbes Murray | Member of Shipwreck Inquiry Board (uncredited) |
| James Nolan | First Diver (uncredited) |
| Frank O'Connor | Old Seaman (uncredited) |
| Gil Perkins | Seaman / Flogger (uncredited) |
| John Pickard | Second Diver (uncredited) |
| George Piltz | Native (uncredited) |
| Norman Rainey | Lawyer (uncredited) |
| Leo C. Richmond | Native Priest (uncredited) |
| Chuck Roberson | Seaman (uncredited) |
| Wallace Scott | Sailor (uncredited) |
| Mickey Simpson | Second Officer (uncredited) |
| Carl Thompson | Hekkim, Cabin Boy (uncredited) |
| Kuka Tuima | Native (uncredited) |
| Harry J. Vejar | Jarma, Angelique's Servant (uncredited) |
| Harlan Warde | Seaman Handling Diving Line (uncredited) |
| John Wengraf | Prosecuting Attorney (uncredited) |
| Harry Wilson | Seaman on 'Red Witch' (uncredited) |
| Ward Wood | Young Sailor (uncredited) |
