| Denzel Washington | Lt. Parker Barnes |
| Kelly Lynch | Madison Carter |
| Russell Crowe | SID 6.7 |
| Stephen Spinella | Lindenmeyer |
| William Forsythe | William Cochran |
| Louise Fletcher | Elizabeth Deane |
| William Fichtner | Wallace |
| Costas Mandylor | John Donovan |
| Kevin J. O'Connor | Clyde Reilly |
| Kaley Cuoco | Karin Carter |
| Christopher Murray | Matthew Grimes |
| Heidi Schanz | Sheila 3.2 |
| Traci Lords | Media Zone Singer |
| Gordon Jennison Noice | Big Red (as J. Gordon Noice) |
| Mari Morrow | Linda Barnes |
| Miracle Vincent | Christine Barnes (as Miracle Unique Vincent) |
| Mara Duronslet | Beautiful Woman at Olympic Stadium |
| Michael Buffer | Emcee |
| Karen Annarino | 'IS' TV Reporter |
| Miguel Nájera | Rafael Debaca |
| Danny Goldring | John Symes |
| Randall Fontana | Ed |
| Allen Scotti | Surgeon |
| Dwayne Chattman | Stripped Man in Media Zone |
| Ed Marques | Blonde Punk in Media Zone |
| Cheryl Lawson | Pretty Woman in Media Zone |
| Kevin Loreque | Animatronic Bartender |
| Eiko Nijo | Geisha Hostess |
| Gaura Vani Buchwald | Burly Man in Video Store (as Gauravani Buchwald) |
| Rolando Molina | Salesman in Videostore |
| Gary Anthony Sturgis | Officer at Video Store |
| Monica Allison | Woman on Train |
| Susan Mohun | Bystander |
| David Asman | Metrolink Cop |
| Anthony C. Hall | Locator Technician |
| Amy Smallman | Aide in Cochran's Office |
| Ahmed Ahmed | Cameraman |
| Marva Hicks | Onscreen Talent |
| Juan A. Riojas | Metromedia Cop |
| Steven R. Barnett | Metromedia Cop |
| John Walcutt | SWAT Captain |
| Michael B. Silver | Undercover Cop (as Michael Buchman) |
| Jordan Marder | Prison Transport Guard |
| Brogan Young | Monitor Prison Guard |
| Laura Leigh Hughes | Suburban Reporter |
| Dustin Nguyen | Suburban Reporter |
| Anthony Winters | Male Newscaster (as Tony Winters) |
| Virginia Watson | Anchorwoman |
| Beverly Cohen | Female Tabloid TV Host |
| Margot Hope | Paula |
| Una Damon | Woman with Video Camera |
| Mary-Rachel Foot | Woman with Video Camera |
| Jennifer Greenhut | Screaming Woman |
| Lesa Noelle | Screaming Woman |
| Michelle Smith | Screaming Woman |
| Brit Thompson | Screaming Woman |
| Alanna Ubach | Eila |
| Kevin La Presle | Paramedic |
| Daniel Anderson | Police Detective |
| Eric Bernt | Building Supervisor |
| Rob Gomes | S.W.A.T. Guy (as Robert John Gomes) |
| Michael Tamburro | Helicopter Pilot |
| Frank Welker | Special Vocal Effects (voice) |
| Richard Atchley | Rowdy Guy at UFC Match (uncredited) |
| Anthony Backman | Metrolink Patron (uncredited) |
| Johnny Kim | Lab Tech (uncredited) |
| Sarah Krasner | Screaming Hostage (uncredited) |
| Ken Shamrock | Ultimate Fighter (uncredited) |
| Rogan Wilde | TV News Producer (uncredited) |
