| Mel Gibson | Lt. Col. Hal Moore |
| Madeleine Stowe | Julie Moore |
| Greg Kinnear | Maj. Bruce 'Snake' Crandall |
| Sam Elliott | Sgt. Maj. Basil Plumley |
| Chris Klein | 2nd Lt. Jack Geoghegan |
| Keri Russell | Barbara Geoghegan |
| Barry Pepper | Joe Galloway |
| Duong Don | Lt. Col. Nguyen Huu An |
| Ryan Hurst | Sgt. Ernie Savage |
| Robert Bagnell | 1st Lt. Charlie Hastings |
| Marc Blucas | 2nd Lt. Henry Herrick |
| Josh Daugherty | Sp4 Robert Ouellette |
| Jsu Garcia | Capt. Tony Nadal |
| Jon Hamm | Capt. Matt Dillon |
| Clark Gregg | Capt. Tom Metsker |
| Desmond Harrington | Sp4 Bill Beck |
| Blake Heron | Sp4 Galen Bungum |
| Erik MacArthur | Sp4 Russell Adams |
| Dylan Walsh | Capt. Robert Edwards |
| Mark McCracken | Capt. Ed 'Too Tall' Freeman |
| Edwin 'EdVanz'd' Morrow | Pfc. Willie Godboldt (as Edwin Morrow) |
| Brian Tee | Pfc. Jimmy Nakayama |
| Sloane Momsen | Cecile Moore |
| Bellamy Young | Catherine Metsker |
| Simbi Khali | Alma Givens (as Simbi Kali Williams) |
| Jim Grimshaw | Maj. Gen. Henry Kinnard |
| Forry Smith | Sfc. Carl Palmer |
| Steven Nelson | Sp5 Charlie 'Doc' Lose |
| Vincent Angell | Capt. Robert 'Doc' Carrera |
| Michael Tomlinson | Col. Tim Brown |
| Keith Szarabajka | Diplomatic Spook |
| Tim Abell | Army Intelligence Officer |
| Patrick St. Esprit | General in Hallway |
| Mike White | Sfc. Bob White, Mortar Sergeant (as Michael John White) |
| Daniel Roebuck | Medevac CO |
| Maia Lien | Army Wife |
| Dan Beene | Cab Driver (as Danny Beene) |
| Taylor Momsen | Julie Moore |
| Joshua McLaurin | Greg Moore (as Josh McLaurin) |
| Devon Werkheiser | Steve Moore |
| Luke Benward | David Moore |
| Billinjer C. Tran | Viet Minh Sergeant |
| Vien Hong | Mr. Nik |
| Joseph Tran | NVA Prisoner |
| Joseph Hieu | NVA Officer |
| Lam Nguyen | NVA Soldier with Bayonet |
| Diep Bui | NVA Wife (as Zoë Bui) |
| Andrew Wallace | French Bugler |
| Nicholas Hosking | French Captain |
| Michael Giordani | French Lieutenant |
| Shepard Koster | Reporter (as Shep Koster) |
| Kate Lombardi | Reporter |
| Ingrid Semler | Reporter |
| Jason Powell | Sgt. Robert Stokes |
| Doug C. Cook | Capt. Ray Lefebvre |
| Sean Bunch | Trooper on Fire (as Sean Thomas Bunch) |
| F. Lee Reynolds | Chopper Crewman |
| Stephen Zapotoczny | Edwards' Radio Operator |
| Frank Kostenko Jr. | Foxhole Trooper |
| Ben Allison | Lt. Cochran (uncredited) |
| Brian Carpenter | Sec. of Defense Robert McNamara (uncredited) |
| Chris Cate | Soldier (uncredited) |
| George Cheung | NVA Officer (uncredited) |
| Cliff Fleming | Capt. Jon Mills (uncredited) |
| Brendan Ford | Jump Coordinator (uncredited) |
| Kelli Franklin | Mrs. Charlie Hastings (uncredited) |
| Christian Gibson | Soldier (uncredited) |
| Justin Gordon | French Officer (uncredited) |
| Lyndon Johnson | Himself (archive footage) (uncredited) |
| Derrell Keith Lester | Black Private (uncredited) |
| Will Klipstine | Private Davey (uncredited) |
| Matthew Lang | 1st Lt. John Arrington (uncredited) |
| Danny Le Boyer | Sergeant (uncredited) |
| Matt Mangum | Pvt. Soprano (uncredited) |
| Johnny Nguyen | Young NVA Lieutenant (uncredited) |
| Randy Oglesby | Lt. Col. List (uncredited) |
| Jonathan Parks Jordan | White Private (uncredited) |
| John Paul Rice | Pvt. John Henry (uncredited) |
| Keni Thomas | Sergeant (uncredited) |
| Phong Atwood Vo | North Vietnamese Soldier - South Vietnamese and vVillager (voice) (uncredited) |
